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Activation of AKT signaling promotes cell growth and survival in α7β1 integrin-mediated alleviation of muscular dystrophy

Transgenic expression of the α7 integrin can ameliorate muscle pathology in a mouse model of Duchenne muscular dystrophy (mdx/utr(−/−)) and thus can compensate for the loss of dystrophin in diseased mice. In spite of the beneficial effects of the α7 integrin in protecting mice from dystrophy, identi...

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Autori principali: Boppart, Marni D., Burkin, Dean J., Kaufman, Stephen J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046458/
https://ncbi.nlm.nih.gov/pubmed/21216283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2011.01.002
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