Mena deficiency delays tumor progression and decreases metastasis in polyoma middle-T transgenic mouse mammary tumors

INTRODUCTION: The actin binding protein Mammalian enabled (Mena), has been implicated in the metastatic progression of solid tumors in humans. Mena expression level in primary tumors is correlated with metastasis in breast, cervical, colorectal and pancreatic cancers. Cells expressing high Mena leve...

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Hauptverfasser: Roussos, Evanthia T, Wang, Yarong, Wyckoff, Jeffrey B, Sellers, Rani S, Wang, Weigang, Li, Jiufeng, Pollard, Jeffrey W, Gertler, Frank B, Condeelis, John S
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046446/
https://ncbi.nlm.nih.gov/pubmed/21108830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2784
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