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Balancing life and death in the ischemic brain: SIK and TORC weigh in
Activation of NMDA receptors during cerebral ischemia triggers signaling pathways that promote both neuronal death and survival. In this issue of Neuron, Sasaki et al. present evidence for a new endogenous survival pathway involving the kinase SIK2 and the CREB coactivator TORC1. The powerful neurop...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3046410/ https://ncbi.nlm.nih.gov/pubmed/21379368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.12.029 |
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