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Anti-CD3 antibody ameliorates experimental autoimmune uveitis by inducing both IL-10 and TGF-β dependent regulatory T cells

Chronic/recurrent autoimmune (idiopathic) uveitis is difficult to treat and they account for approximately 10% of legal blindness in the Western world. As it has been reported that anti-CD3 antibody can enhance T cell regulatory function, we investigated its effects in vivo on experimental autoimmun...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ke, Yan, Jiang, Guomin, Sun, Deming, Kaplan, Henry J., Shao, Hui
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046397/
https://ncbi.nlm.nih.gov/pubmed/21256812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2010.12.016
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