Hepatic Deletion of Smad7 in Mouse Leads to Spontaneous Liver Dysfunction and Aggravates Alcoholic Liver Injury

BACKGROUND: TGF-β has been known to play an important role in various liver diseases including fibrosis and alcohol-induced fatty liver. Smad7 is an intracellular negative regulator of TGF-β signaling. It is currently unclear whether endogenous Smad7 has an effect on liver function and alcoholic liv...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Zhu, Lu, Wang, Lingdi, Wang, Xiao, Luo, Xiaolin, Yang, Ling, Zhang, Rui, Yin, Hongkun, Xie, Dong, Pan, Yi, Chen, Yan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2011
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046253/
https://ncbi.nlm.nih.gov/pubmed/21386907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017415
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