Unusual conformational effect exerted by Z-DNA upon its neighboring sequences.

Supercoiled plasmid DNA harboring an insert of (dG-dC)16, a sequence known to form Z-DNA upon negative supercoiling, was reacted with chloroacetaldehyde. Chloroacetaldehyde, like bromoacetaldehyde, was found to be a specific probe for detecting unpaired DNA bases in supercoiled plasmid DNA. Under to...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Kohwi-Shigematsu, T, Manes, T, Kohwi, Y
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1987
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304621/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3470786/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.8.2223
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