Unusual conformational effect exerted by Z-DNA upon its neighboring sequences.
Supercoiled plasmid DNA harboring an insert of (dG-dC)16, a sequence known to form Z-DNA upon negative supercoiling, was reacted with chloroacetaldehyde. Chloroacetaldehyde, like bromoacetaldehyde, was found to be a specific probe for detecting unpaired DNA bases in supercoiled plasmid DNA. Under to...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1987
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304621/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3470786/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.8.2223 |
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