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Elimination of Endogenous Toxin, Creatinine from Blood Plasma Depends on Albumin Conformation: Site Specific Uremic Toxicity & Impaired Drug Binding

Uremic syndrome results from malfunctioning of various organ systems due to the retention of uremic toxins which, under normal conditions, would be excreted into the urine and/or metabolized by the kidneys. The aim of this study was to elucidate the mechanisms underlying the renal elimination of ure...

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Main Authors: Varshney, Ankita, Rehan, Mohd, Subbarao, Naidu, Rabbani, Gulam, Khan, Rizwan Hasan
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046181/
https://ncbi.nlm.nih.gov/pubmed/21386972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017230
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