Gene expression profiling of oxidative stress response of C. elegans aging defective AMPK mutants using massively parallel transcriptome sequencing

BACKGROUND: A strong association between stress resistance and longevity in multicellular organisms has been established as many mutations that extend lifespan also show increased resistance to stress. AAK-2, the C. elegans homolog of an alpha subunit of AMP-activated protein kinase (AMPK) is an int...

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Detalhes bibliográficos
Main Authors: Shin, Heesun, Lee, Hyojin, Fejes, Anthony P, Baillie, David L, Koo, Hyeon-Sook, Jones, Steven JM
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045954/
https://ncbi.nlm.nih.gov/pubmed/21303547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-4-34
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