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Dendritic vulnerability in neurodegenerative disease: insights from analyses of cortical pyramidal neurons in transgenic mouse models

In neurodegenerative disorders, such as Alzheimer’s disease, neuronal dendrites and dendritic spines undergo significant pathological changes. Because of the determinant role of these highly dynamic structures in signaling by individual neurons and ultimately in the functionality of neuronal network...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Luebke, Jennifer I., Weaver, Christina M., Rocher, Anne B., Rodriguez, Alfredo, Crimins, Johanna L., Dickstein, Dara L., Wearne, Susan L., Hof, Patrick R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045830/
https://ncbi.nlm.nih.gov/pubmed/20177698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00429-010-0244-2
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