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A Blocker of N- and T-type Voltage-Gated Calcium Channels Attenuates Ethanol-Induced Intoxication, Place Preference, Self-Administration, and Reinstatement

There is a clear need for new therapeutics to treat alcoholism. Here, we test our hypothesis that selective inhibitors of neuronal calcium channels will reduce ethanol consumption and intoxication, based on our previous studies using knock-out mice and cell culture systems. We demonstrate that pretr...

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Main Authors: Newton, Philip M., Zeng, Lily, Wang, Victoria, Connolly, Jacklyn, Wallace, Melisa J., Kim, Chanki, Shin, Hee-Sup, Belardetti, Francesco, Snutch, Terrance P., Messing, Robert O.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045811/
https://ncbi.nlm.nih.gov/pubmed/18987207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3621-08.2008
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