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RNA interference-mediated knockdown of CD49e (α5 integrin chain) in human thymic epithelial cells modulates the expression of multiple genes and decreases thymocyte adhesion

BACKGROUND: The thymus is a central lymphoid organ, in which bone marrow-derived T cell precursors undergo a complex process of maturation. Developing thymocytes interact with thymic microenvironment in a defined spatial order. A component of thymic microenvironment, the thymic epithelial cells, is...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Linhares-Lacerda, Leandra, Ribeiro-Alves, Marcelo, Nogueira, Ana Cristina Martins de Almeida, Mendes-da-Cruz, Daniella Areas, Magalhães, Danielle Aparecida, Dardenne, Mireille, Passos, Geraldo Aleixo, Savino, Wilson
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BioMed Central 2010
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045795/
https://ncbi.nlm.nih.gov/pubmed/21210968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-S5-S2
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