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Primary trastuzumab resistance: new tricks for an old drug
Trastuzumab (Herceptin®) is the first FDA-approved therapeutic targeting a HER-family receptor tyrosine kinase (HER2/ErbB2/neu). Although trastuzumab is effective in the treatment of HER2-positive breast cancer, a substantial proportion of patients will not respond to trastuzumab-based regimens (pri...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3045786/ https://ncbi.nlm.nih.gov/pubmed/20973799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2010.05782.x |
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