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One allele's loss is another's gain: Alterations of NKX2-8 in non-small cell lung cancer

Large scale genetic changes such as loss or gain of chromosomes are important drivers of solid tumor carcinogenesis. Recent technological advances in genomic profiling have allowed quantitative detection of gene copy numbers, leading to identification of the 14q13.3 gene locus as functionally import...

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Autors principals: Neal, Joel W., Shaw, Alice
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045701/
https://ncbi.nlm.nih.gov/pubmed/21163872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-3081
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