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Bach1 gene ablation reduces steatohepatitis in mouse MCD diet model
Bach1 is a transcriptional repressor of heme oxygenase-1 (HO-1, a.k.a. HSP-32), which is an inducible enzyme and has anti-oxidation/anti-inflammatory properties shown in various models of organ injuries. Since oxidative stress plays a pivotal role in the pathogenesis of nonalcoholic steatohepatitis...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
the Society for Free Radical Research Japan
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3045690/ https://ncbi.nlm.nih.gov/pubmed/21373270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.09-122GFR |
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