The congenital goiter mutation is linked to the thyroglobulin gene in the mouse.
Rat thyroglobulin (TG) cDNA clones were used to identify DNA restriction fragment variants among inbred mouse strains. One of these variants was shown to be closely linked to the recessive mutation congenital goiter (cog), which had previously been mapped to mouse chromosome 15. These results indica...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1987
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304567/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2882514/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.7.1986 |
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