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Nigrostriatal denervation changes the effect of cannabinoids on subthalamic neuronal activity in rats

RATIONALE: It is known that dopaminergic cell loss leads to increased endogenous cannabinoid levels and CB1 receptor density. OBJECTIVE: The aim of this study was to evaluate the influence of dopaminergic cell loss, induced by injection of 6-hydroxydopamine, on the effects exerted by cannabinoid ago...

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Detalhes bibliográficos
Main Authors: Morera-Herreras, Teresa, Ruiz-Ortega, José Ángel, Linazasoro, Gurutz, Ugedo, Luisa
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045509/
https://ncbi.nlm.nih.gov/pubmed/20959968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-010-2043-0
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