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Paraoxonase 1 (PON1) Status and Substrate Hydrolysis

Paraoxonase 1 (PON1) hydrolyzes a number of organophosphorus (OP) compounds including insecticides and nerve agents. The in vivo efficacy of PON1 to protect against a specific OP exposure depends on the catalytic efficiency of hydrolysis. The Q192R polymorphism affects the catalytic efficiency of hy...

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Bibliografiske detaljer
Main Authors: Richter, Rebecca J., Jarvik, Gail P., Furlong, Clement E.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045428/
https://ncbi.nlm.nih.gov/pubmed/19071155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2008.11.001
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