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Human Pluripotent Stem Cells Differentiated in Fully Defined Medium Generate Hematopoietic CD34(+) and CD34(−) Progenitors with Distinct Characteristics

BACKGROUND: Differentiation of pluripotent stem cells in vitro provides a powerful means to investigate early developmental fates, including hematopoiesis. In particular, the use of a fully defined medium (FDM) would avoid biases induced by unidentified factors contained in serum, and would also all...

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Detalhes bibliográficos
Main Authors: Chicha, Laurie, Feki, Anis, Boni, Alessandro, Irion, Olivier, Hovatta, Outi, Jaconi, Marisa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045374/
https://ncbi.nlm.nih.gov/pubmed/21364915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014733
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