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Using Genomic Sequencing for Classical Genetics in E. coli K12

We here develop computational methods to facilitate use of 454 whole genome shotgun sequencing to identify mutations in Escherichia coli K12. We had Roche sequence eight related strains derived as spontaneous mutants in a background without a whole genome sequence. They provided difference tables ba...

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Detalhes bibliográficos
Main Authors: Lyons, Eric, Freeling, Michael, Kustu, Sydney, Inwood, William
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045373/
https://ncbi.nlm.nih.gov/pubmed/21364914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016717
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