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Exploring the Evolutionary Relationship of Insulin Receptor Substrate Family Using Computational Biology

Insulin receptor substrate (IRS) harbors proteins such as IRS1, IRS2, IRS3, IRS4, IRS5 and IRS6. These key proteins act as vital downstream regulators in the insulin signaling pathway. However, little is known about the evolutionary relationship among the IRS family members. This study explores the...

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Autori principali: Chakraborty, Chiranjib, Agoramoorthy, Govindasamy, Hsu, Minna J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045367/
https://ncbi.nlm.nih.gov/pubmed/21364910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016580
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