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Exploring the Evolutionary Relationship of Insulin Receptor Substrate Family Using Computational Biology

Insulin receptor substrate (IRS) harbors proteins such as IRS1, IRS2, IRS3, IRS4, IRS5 and IRS6. These key proteins act as vital downstream regulators in the insulin signaling pathway. However, little is known about the evolutionary relationship among the IRS family members. This study explores the...

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Autors principals: Chakraborty, Chiranjib, Agoramoorthy, Govindasamy, Hsu, Minna J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045367/
https://ncbi.nlm.nih.gov/pubmed/21364910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016580
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