Problems and challenges in the development and validation of human cell-based assays to determine nanoparticle-induced immunomodulatory effects

BACKGROUND: With the increasing use of nanomaterials, the need for methods and assays to examine their immunosafety is becoming urgent, in particular for nanomaterials that are deliberately administered to human subjects (as in the case of nanomedicines). To obtain reliable results, standardised in...

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Detalhes bibliográficos
Main Authors: Oostingh, Gertie J, Casals, Eudald, Italiani, Paola, Colognato, Renato, Stritzinger, René, Ponti, Jessica, Pfaller, Tobias, Kohl, Yvonne, Ooms, Daniëlla, Favilli, Flavia, Leppens, Hilde, Lucchesi, Davide, Rossi, François, Nelissen, Inge, Thielecke, Hagen, Puntes, Victor F, Duschl, Albert, Boraschi, Diana
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Methodology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045340/
https://ncbi.nlm.nih.gov/pubmed/21306632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-8977-8-8
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