Genesis of Phase-3 Early Afterdepolarizations and Triggered Activity in Acquired Long QT Syndrome

BACKGROUND: Both phase-2 and phase-3 early afterdepolarizations (EADs) occur in long QT syndromes, but their respective roles in generating arrhythmias in intact cardiac tissue are incompletely understood. METHODS AND RESULTS: Intracellular Ca (Ca(i)) and membrane voltage (V(m)) were optically mappe...

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Hauptverfasser: Maruyama, Mitsunori, Lin, Shien-Fong, Xie, Yuanfang, Chua, Su-Kiat, Joung, Boyoung, Han, Seongwook, Shinohara, Tetsuji, Shen, Mark J., Qu, Zhilin, Weiss, James N., Chen, Peng-Sheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045276/
https://ncbi.nlm.nih.gov/pubmed/21078812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.110.959064
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