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Multicopy plasmid with a structure related to the polyoma virus genome.

In a subclone derived from mouse L(tk-) cells, we found a plasmid present in a high copy number (greater than 5000 copies per cell) that was stably maintained extrachromosomally without any cytopathic effect to the host cells. This plasmid, termed L factor, has two forms: 5.3 and 5.5 kilobase pairs....

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Kusano, T, Uehara, H, Saito, H, Segawa, K, Oishi, M
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1987
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304526/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3031650/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.7.1789
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