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Detecting Departure From Additivity Along a Fixed-Ratio Mixture Ray With a Piecewise Model for Dose and Interaction Thresholds
For mixtures of many chemicals, a ray design based on a relevant, fixed mixing ratio is useful for detecting departure from additivity. Methods for detecting departure involve modeling the response as a function of total dose along the ray. For mixtures with many components, the interaction may be d...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3045205/ https://ncbi.nlm.nih.gov/pubmed/21359103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13253-010-0030-x |
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