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Detecting Departure From Additivity Along a Fixed-Ratio Mixture Ray With a Piecewise Model for Dose and Interaction Thresholds

For mixtures of many chemicals, a ray design based on a relevant, fixed mixing ratio is useful for detecting departure from additivity. Methods for detecting departure involve modeling the response as a function of total dose along the ray. For mixtures with many components, the interaction may be d...

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Detalhes bibliográficos
Main Authors: Yeatts, Sharon D., Gennings, Chris, Wagner, Elizabeth D., Simmons, Jane Ellen, Plewa, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045205/
https://ncbi.nlm.nih.gov/pubmed/21359103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13253-010-0030-x
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