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Role of sialic acid in synaptosomal transport of amino acid transmitters.

Active, high-affinity, sodium-dependent uptake of gamma-aminobutyric acid and of the acidic amino acid D-aspartate was inhibited by pretreatment of synaptosomes with neuraminidase from Vibrio cholerae. Inhibition was of a noncompetitive type and was related to the amount of sialic acid released. The...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Zaleska, M M, Erecińska, M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304506/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3470752/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.6.1709
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