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Human salivary gustin is a potent activator of calmodulin-dependent brain phosphodiesterase.

Human salivary gustin stimulated activity of brain calmodulin-dependent cyclic nucleotide phosphodiesterase (cAMP PDEase; 3',5'-cyclic-nucleotide phosphodiesterase, EC 3.1.4.17) in a dose-dependent manner in the absence of calmodulin. At physiological levels found in human saliva, gustin activated c...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Law, J S, Nelson, N, Watanabe, K, Henkin, R I
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1987
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304499/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3031646/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.6.1674
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