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Vav Family Rho Guanine Nucleotide Exchange Factors Regulate CD36-mediated Macrophage Foam Cell Formation

Lipid-laden macrophages or “foam cells” are the primary components of the fatty streak, the earliest atherosclerotic lesion. Although Vav family guanine nucleotide exchange factors impact processes highly relevant to atherogenesis and are involved in pathways common to scavenger receptor CD36 signal...

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Autors principals: Rahaman, S. Ohidar, Swat, Wojciech, Febbraio, Maria, Silverstein, Roy L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044957/
https://ncbi.nlm.nih.gov/pubmed/21209086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.192450
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