Anti-Group A Streptococcal Vaccine Epitope: STRUCTURE, STABILITY, AND ITS ABILITY TO INTERACT WITH HLA CLASS II MOLECULES

Streptococcus pyogenes infections remain a health problem in several countries due to poststreptococcal sequelae. We developed a vaccine epitope (StreptInCor) composed of 55 amino acids residues of the C-terminal portion of the M protein that encompasses both T and B cell protective epitopes. The nu...

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Detalhes bibliográficos
Main Authors: Guilherme, Luiza, Alba, Martha P., Ferreira, Frederico Moraes, Oshiro, Sandra Emiko, Higa, Fabio, Patarroyo, Manuel E., Kalil, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044955/
https://ncbi.nlm.nih.gov/pubmed/21169359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.132118
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