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Age-dependent gain of alternative splice forms and biased duplication explain the relation between splicing and duplication

We analyze here the relation between alternative splicing and gene duplication in light of recent genomic data, with a focus on the human genome. We show that the previously reported negative correlation between level of alternative splicing and family size no longer holds true. We clarify this patt...

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Bibliografiske detaljer
Main Authors: Roux, Julien, Robinson-Rechavi, Marc
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044850/
https://ncbi.nlm.nih.gov/pubmed/21173032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.113803.110
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