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Rapid stimulation by insulin of a serine/threonine kinase in 3T3-L1 adipocytes that phosphorylates microtubule-associated protein 2 in vitro.

Insulin treatment (Kact, 5 X 10(-9) M) of serum-starved 3T3-L1 adipocytes stimulates a soluble serine/threonine kinase that catalyzes phosphorylation of microtubule-associated protein 2 (MAP-2) in vitro. Maximal activation of MAP-2 kinase activity by 80 nM insulin was observed after 10 min of hormon...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Ray, L B, Sturgill, T W
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1987
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304462/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2951732/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.6.1502
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