Aldosterone activates Na+/H+ exchange and raises cytoplasmic pH in target cells of the amphibian kidney.

The hypothesis was tested if the mineralocorticoid hormone aldosterone stimulates Na+/H+ exchange in "giant cells" fused from individual target cells of the distal nephron of the frog kidney. By means of microelectrodes, steady-state intracellular pH (pHi) and pHi recovery from an acid load were rec...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Oberleithner, H, Weigt, M, Westphale, H J, Wang, W
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1987
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304451/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3029782/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.5.1464
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