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TRAF3 is required for T cell-mediated immunity and T cell receptor/CD28 signaling

We recently reported that TRAF3, a ubiquitously expressed adaptor protein, promotes mature B cell apoptosis. However, the specific function of TRAF3 in T cells has remained unclear. Here we report the generation and characterization of T cell-specific TRAF3(−/−) mice, in which the TRAF3 gene was del...

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Detalhes bibliográficos
Main Authors: Xie, Ping, Kraus, Zachary J., Stunz, Laura L., Liu, Yan, Bishop, Gail A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044490/
https://ncbi.nlm.nih.gov/pubmed/21084666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000290
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