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TRAF3 is required for T cell-mediated immunity and T cell receptor/CD28 signaling
We recently reported that TRAF3, a ubiquitously expressed adaptor protein, promotes mature B cell apoptosis. However, the specific function of TRAF3 in T cells has remained unclear. Here we report the generation and characterization of T cell-specific TRAF3(−/−) mice, in which the TRAF3 gene was del...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3044490/ https://ncbi.nlm.nih.gov/pubmed/21084666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000290 |
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