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Aberrant splicing of proteolipid protein mRNA in the dysmyelinating jimpy mutant mouse.

cDNA clones encoding proteolipid protein (PLP) were isolated from a mouse brain library and sequenced. We describe two transcripts arising from the PLP locus by alternative splicing: the major one encodes the 277-amino acid PLP protein and the minor one corresponds to the DM-20 protein, a PLP-like p...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Hudson, L D, Berndt, J A, Puckett, C, Kozak, C A, Lazzarini, R A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304449/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3469678/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.5.1454
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