Aberrant splicing of proteolipid protein mRNA in the dysmyelinating jimpy mutant mouse.

cDNA clones encoding proteolipid protein (PLP) were isolated from a mouse brain library and sequenced. We describe two transcripts arising from the PLP locus by alternative splicing: the major one encodes the 277-amino acid PLP protein and the minor one corresponds to the DM-20 protein, a PLP-like p...

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Bibliographic Details
Main Authors: Hudson, L D, Berndt, J A, Puckett, C, Kozak, C A, Lazzarini, R A
Format: Artigo
Language:Inglês
Published: 1987
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC304449/
https://ncbi.nlm.nih.gov/pubmed/3469678
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