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Skint-1 is a highly specific, unique selecting component for epidermal T cells
αβ T-cell repertoire selection is mediated by peptide–MHC complexes presented by thymic epithelial or myeloid cells, and by lipid–CD1 complexes expressed by thymocytes. γδ T-cell repertoire selection, by contrast, is largely unresolved. Mice mutant for Skint-1, a unique Ig superfamily gene, do not d...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3044407/ https://ncbi.nlm.nih.gov/pubmed/21300860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010890108 |
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