Corepressor SMRT promotes oxidative phosphorylation in adipose tissue and protects against diet-induced obesity and insulin resistance

The ligand-dependent competing actions of nuclear receptor (NR)-associated transcriptional corepressor and coactivator complexes allow for the precise regulation of NR-dependent gene expression in response to both temporal and environmental cues. Here we report the mouse model termed silencing media...

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Hlavní autoři: Fang, Sungsoon, Suh, Jae Myoung, Atkins, Annette R., Hong, Suk-Hyun, Leblanc, Mathias, Nofsinger, Russell R., Yu, Ruth T., Downes, Michael, Evans, Ronald M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2011
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044388/
https://ncbi.nlm.nih.gov/pubmed/21300871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017707108
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