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Structural dependence of HET-s amyloid fibril infectivity assessed by cryoelectron microscopy

HET-s is a prion protein of the fungus Podospora anserina which, in the prion state, is active in a self/nonself recognition process called heterokaryon incompatibility. Its prionogenic properties reside in the C-terminal “prion domain.” The HET-s prion domain polymerizes in vitro into amyloid fibri...

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Detalhes bibliográficos
Main Authors: Mizuno, Naoko, Baxa, Ulrich, Steven, Alasdair C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044374/
https://ncbi.nlm.nih.gov/pubmed/21300906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011342108
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