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Synthetic gene construct expressing a repeated and highly immunogenic epitope of the Plasmodium falciparum antigen Pf155.

The Plasmodium falciparum-derived antigen Pf155 contains two blocks of tandemly repeated amino acid sequences. A pair of complementary oligonucleotides, encoding the C-terminally located repeat Val-Glu-His-Asp-Ala-Glu-Glu-Asn, were synthesized. The oligonucleotides were polymerized by ligation, and...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Aslund, L, Sjölander, A, Wahlgren, M, Wåhlin, B, Ruangjirachuporn, W, Berzins, K, Wigzell, H, Perlmann, P, Pettersson, U
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1987
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304437/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2434955/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.5.1399
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