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Experimental and clinical evidence for modification of hepatic ischaemia–reperfusion injury by N-acetylcysteine during major liver surgery

BACKGROUND: Hepatic ischaemia–reperfusion (I/R) injury occurs in both liver resectional surgery and in transplantation. The biochemistry of I/R injury involves short-lived oxygen free radicals. N-acetylcysteine (NAC) is a thiol-containing synthetic compound used in the treatment of acetaminophen tox...

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Detalhes bibliográficos
Main Authors: Jegatheeswaran, Santhalingam, Siriwardena, Ajith K
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044340/
https://ncbi.nlm.nih.gov/pubmed/21241423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1477-2574.2010.00263.x
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