Adult Murine Bone Marrow-Derived Very Small Embryonic-Like Stem Cells (VSELs) Differentiate Into the Hematopoietic Lineage After Co-Culture Over OP9 Stromal Cells

OBJECTIVE: We recently identified a population of small Sca-1(+)/Lin(−)/CD45(−) cells in adult murine bone marrow that express several epiblast/germ line and pluripotent stem cell markers (e.g., Oct-4 and SSEA-4) that we named “very small embryonic-like stem cells” (VSELs). In this report, we test t...

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Hauptverfasser: Ratajczak, Janina, Wysoczynski, Marcin, Zuba-Surma, Ewa, Wan, Wu, Kucia, Magda, Yoder, Mervin C., Ratajczak, Mariusz Z.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044339/
https://ncbi.nlm.nih.gov/pubmed/21034791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2010.10.007
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