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A regression analysis of gene expression in ES cells reveals two gene classes that are significantly different in epigenetic patterns

BACKGROUND: To understand the gene regulatory system that governs the self-renewal and pluripotency of embryonic stem cells (ESCs) is an important step for promoting regenerative medicine. In it, the role of several core transcription factors (TFs), such as Oct4, Sox2 and Nanog, has been intensively...

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Detalhes bibliográficos
Main Authors: Park, Sung-Joon, Nakai, Kenta
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044308/
https://ncbi.nlm.nih.gov/pubmed/21342583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-S1-S50
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