Transfection of a rearranged viral DNA fragment, WZhet, stably converts latent Epstein-Barr viral infection to productive infection in lymphoid cells.

An Epstein-Barr viral gene (ZEBRA) is identified that, in human lymphoblastoid cells, activates a switch causing the virus to shift from the latent to the replicative phase of its life cycle. We have shown that a 2.7-kilobase-pair rearranged Epstein-Barr virus DNA fragment of this gene (BamHI fragme...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Grogan, E, Jenson, H, Countryman, J, Heston, L, Gradoville, L, Miller, G
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1987
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Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304422/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3029778/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.5.1332
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