Longitudinal Study of Primary HIV-1 Isolates in Drug-Naïve Individuals Reveals the Emergence of Variants Sensitive to Anti-HIV-1 Monoclonal Antibodies

To study how virus evolution affects neutralization sensitivity and to determine changes that occur in and around epitopes, we tested the ability of 13 anti-HIV-1 gp120 (anti-V2, anti-V3, anti-CD4bd and anti-carbohydrate) human monoclonal antibodies (mAbs) to neutralize sequential viruses obtained f...

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Main Authors: Haldar, Bijayesh, Burda, Sherri, Williams, Constance, Heyndrickx, Leo, Vanham, Guido, Gorny, Miroslaw K., Nyambi, Phillipe
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044167/
https://ncbi.nlm.nih.gov/pubmed/21383841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017253
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