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Convection and Retro-Convection Enhanced Delivery: Some Theoretical Considerations Related to Drug Targeting

Delivery of drugs and macromolecules into the brain is a challenging problem, due in part to the blood–brain barrier. In this article, we focus on the possibilities and limitations of two infusion techniques devised to bypass the blood–brain barrier: convection enhanced delivery (CED) and retro-conv...

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Main Authors: Motion, J. P. Michael, Huynh, Grace H., Szoka, Francis C., Siegel, Ronald A.
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044083/
https://ncbi.nlm.nih.gov/pubmed/20963628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-010-0296-2
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