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Alteration of the tumorigenic and metastatic properties of neoplastic cells is associated with the process of calcium phosphate-mediated DNA transfection.

During the course of studies designed to assess the effect of human Ha-ras gene expression on the malignant behavior of transfected mouse tumor cells we noted that the process of Ca3(PO4)2-mediated DNA transfection was itself associated with profound alterations in tumorigenic or metastatic behavior...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Kerbel, R S, Waghorne, C, Man, M S, Elliott, B, Breitman, M L
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1987
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304407/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3469668/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.5.1263
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