Relative roles of doxycycline and cation chelation in endothelial glycan shedding and adhesion of leukocytes

Leukocyte [white blood cell (WBC)] adhesion and shedding of glycans from the endothelium [endothelial cells (ECs)] in response to the chemoattractant f-Met-Leu-Phe (fMLP) has been shown to be attenuated by topical inhibition of matrix metalloproteases (MMPs) with doxycycline (Doxy). Since Doxy also...

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Hlavní autoři: Lipowsky, Herbert H., Sah, Rachna, Lescanic, Anne
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2011
Témata:
Vascular Biology and Microcirculation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044056/
https://ncbi.nlm.nih.gov/pubmed/21148759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00923.2010
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