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A Reversible Aptamer Improves Outcome and Safety in Murine Models of Stroke and Hemorrhage
Treatment of acute ischemic stroke with intravenous tissue-type plasminogen activator is underutilized partly due to the risk of life-threatening hemorrhage. In response to the clinical need for safer stroke therapy, we explored using an aptamer-based therapeutic strategy to promote cerebral reperfu...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Mary Ann Liebert, Inc.
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3043993/ https://ncbi.nlm.nih.gov/pubmed/21142878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/oli.2010.0262 |
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