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Engineered Three-Dimensional Liver Mimics Recapitulate Critical Rat-Specific Bile Acid Pathways

A critical hepatic function is the maintenance of optimal bile acid (BA) compositions to achieve cholesterol homeostasis. BAs are rarely quantified to assess hepatic phenotype in vitro since existing analytical techniques have inadequate resolution. We report a detailed investigation into the biosyn...

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Autori principali: Detzel, Christopher J., Kim, Yeonhee, Rajagopalan, Padmavathy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043955/
https://ncbi.nlm.nih.gov/pubmed/20929286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2010.0423
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