A promoterless retroviral vector indicates that there are sequences in U3 required for 3' RNA processing.

We constructed a retrovirus vector in which all viral transcriptional signals are deleted during provirus formation. This vector would be safer and more useful in gene-transfer experiments. Construction of this vector involved the deletion of all of the U3 sequence except for 10 base pairs, required...

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Bibliographic Details
Main Authors: Dougherty, J P, Temin, H M
Format: Artigo
Language:Inglês
Published: 1987
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC304393/
https://ncbi.nlm.nih.gov/pubmed/3029769
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