Site-directed mutagenesis of the COOH-terminal region of colicin A: effect on secretion and voltage-dependent channel activity.

A large number of mutants introducing point mutations and deletions into the COOH-terminal domain of colicin A have been constructed by using site-directed mutagenesis. The COOH-terminal domain carries the channel activity. The effects of the alterations in the polypeptide chain on the secretion of...

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Autors principals: Baty, D, Knibiehler, M, Verheij, H, Pattus, F, Shire, D, Bernadac, A, Lazdunski, C
Format: Artigo
Idioma:Inglês
Publicat: 1987
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC304384/
https://ncbi.nlm.nih.gov/pubmed/2434951
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